- ￥2800
- Tanda
- TD-26453
- 美国
- 2025年11月27日
- ELISA, WB, IHC
- Mouse
- 脊椎动物
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- 详细信息
- 技术资料
- 供应商：
武汉天德
- 库存：
999
- 靶点：
SMAD4, DPC4, JIP, MADH4, MYHRS
- 级别：
科研级
- 目录编号：
TD-26453
- 克隆性：
单克隆
- 抗原来源：
蛋白
- 保质期：
24个月
- 抗体英文名：
Anti-SMAD4 Mouse Monoclonal Antibody
- 抗体名：
SMAD4
- 标记物：
FITC
- 宿主：
Mouse
- 适应物种：
脊椎动物
- 免疫原：
Purified SMAD4 protein, human origin.
- 亚型：
IgG
- 形态：
液体
- 应用范围：
ELISA, WB, IHC
- 保存条件：
-20℃
- 浓度：
1mg/ml
- 规格：
100μl
SMAD4 Monoclonal Antibody
| Cat. #: TD-26453 |
| Gene Symbol: SMAD4, DPC4, JIP, MADH4, MYHRS |
| Description: Anti-SMAD4 Mouse Monoclonal Antibody |
| Background: SMAD4 family member 4, also known as SMAD4, is a protein that in human is encoded by the SMAD4 gene. It is often found mutated in many cancers. It acts as a tumor suppressor that functions in the regulation of the TGF-β signal transduction pathway, which negatively regulates growth of epithelial cells and the extracellular matrix (ECM). SMAD4 alterations have been found in multiploid colorectal cancer and pancreatic carcinoma. It is found inactivated in at least 50% of pancreatic cancers. It is also found mutated in the autosomal dominant disease juvenile polyposis syndrome (JPS). |
| Immunogen: Purified SMAD4 protein, human origin. . |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA: 1:1000-1:2000 WB: 1:500-1:1000 IHC: 1:50-1:100 |
| Concentration: 1 mg/ml |
| Host Species: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes SMAD4 of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot:  Western blot analysis of recombinant SMAD4 protein. Purified His-tagged SMAD4 protein (1-552aa, 65kd) and was blotted with anti-SMAD4 monoclonal antibody (Cat. #TD-26453). Immunofluorescence:  Immunofluorescence of cells expressing SMAD4 proteins with anti SMAD4 antibody. HEK293T cells were transfected with pCDNA3-GFP-SMAD4 (WT) plasmid, then fixed and stained with anti SMAD4 monoclonal antibody (Cat. #TD-26453). |
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SMAD4
￥2800
