- ￥4800
- Tanda
- 美国
- TD-26158
- 2026年01月20日
- ELISA, WB, IHC
- Mouse
- 脊椎动物
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A synthetic peptide from the internal region of STK, which includes the mutation of P281L, human origin.
- 亚型：
IgG
- 形态：
液体
- 保存条件：
-20℃
- 克隆性：
单克隆
- 标记物：
FITC
- 适应物种：
脊椎动物
- 保质期：
24个月
- 抗原来源：
蛋白
- 目录编号：
TD-26158
- 级别：
科研级
- 库存：
999
- 供应商：
武汉天德
- 宿主：
Mouse
- 应用范围：
ELISA, WB, IHC
- 浓度：
0.5mg/ml
- 靶点：
STK11
- 抗体英文名：
Anti STK11 Mouse Monoclonal Antibody
- 抗体名：
STK11 Antibody
- 规格：
100μl
STK11 Antibody
| Cat. #: TD-26158 |
| Size: 100 µL |
| Gene Symbol: STK11, LKB1, PJS, hLKB1 |
| Description: Anti-STK11 Mouse Monoclonal Antibody |
| Background: Serine/threonine kinase 11 (STK11) also known as liver kinase B1 (LKB1) or renal carcinoma antigen NY-REN-19 is a kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response, and functions as a tumour suppressor. Recent studies have uncovered a large number of somatic mutations of the STK11 gene that are present in lung, cervical, breast, intestinal, testicular, pancreatic and skin cancer. |
| Immunogen: A synthetic peptide from the internal region of STK, which includes the mutation of P281L, human origin. |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:100-1:1000 IHC: 1:50-1:200 |
| Concentration: 0.5 mg/ml |
| Host Species: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes P281L mutated, but not wild type STK11 of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Immunofluorescence:
 |
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文献和实验17 Direct Sequencing for Peutz-Jeghers Gene LKB1 (STK11) Mutations
While Peutz-Jeghers syndrome (PJS) has been acknowledged as a clinical entity for decades (1 ,2 ), the molecular background for the disease has been unraveled only very recently. PJS has two cardinal features: First, many but not all patients
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
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