Recombinant Human papillomavir

Analysis of E7/Rb Associations

The product of the early gene E7 is one of the major transforming proteins of human papillomaviruses (HPVs). It exerts its activity by associating with and altering the biological functions of several cellular proteins involved in the control

Selective Silencing of Viral Gene E6 and E7 Expression in HPV-Positive Human Cervical Carcinoma Cells Using Small Interfering RNAs

cancer cells as a model, we demonstrate RNAi for viral oncogenes Cervical cancer is the second most common cancer in women worldwide and is caused by human papillomavirus (HPV). Silencing of HPV E6 and E7 gene expression was achieved using siRNAs

Human Papillomavirus Detection by PCR and Typing by Dot-Blot

and (2) late-expressing genes, and (3) a noncoding upstream regulatory region (URR) (Fig. 1 ). The early region is downstream of the URR and consist of six open reading frames (ORFs) (El, E2, E4, E5, E6, and E7). El encodes a DNA binding protein involved