Recombinant Human Interferon R

MicroRNA Expression Profiling by Bead Array Technology in Human Tumor Cell Lines Treated with Interferon-Alpha-2a

to antiproliferative effects of interferons (IFNs). The cause of this variation has been under investigation for more than 40 years, but only basic regulatory mechanisms of interferon signaling are understood today. Small regulatory genome encoded RNAs

Introduction of human 14-3-3 proteins

of Pseudomonas aeruginosa as does bovine brain factor activating exoenzyme S (FAS),which is itself a member of 14-3-3 proteins.In addition,GF14 omega binds calcium,as does the human 14-3-3 homologue reported to be a phospholipase A2.These results indicate

【进展|热点】PD-1信号通过上调BATF抑制HIV特异性CD8阳性T细胞的功能

，探寻到3个特异性表达上调的转录因子：BATF, signal transducer and activator of transcription-1 (STAT1)和interferon regulatory factor-9 (IRF9)。采用构建BATF过表达载体转染T细胞，并应用siRNA策略考察BATF蛋白对T细胞分泌相应细胞因子能力的影响，深入探讨了BATF分子的生物学功能及其与HIV特异性T细胞活性之间的关系。文章认为，PD-1介导的抑制性信号除了可以降低TCR传导的特异性刺激信号