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文献和实验Using BLAT to Find Sequence Similarity in Closely Related Genomes
a protein sequence to identify the coding regions in a genomic sequence and to search for gene family members in the same species, and using a protein sequence to find homologs in another species. Curr. Protoc. Bioinform. 37:10.8.1?10.8.24. © 2012 by John
Obtaining Comparative Genomic Data with the VISTA Family of Computational Tools
from different species is a fundamental method for identifying functional elements, such as exons or enhancers, as they tend to exhibit significant sequence similarity due to purifying selection. Availability of whole?genome sequences for a constantly growing
Mouse Strains and Genetic Nomenclature
. We also provide some guidance to make the best possible choice when establishing an experimental protocol. Curr. Protoc. Mouse Biol. 1:213?238. © 2011 by John Wiley & Sons, Inc. Keywords: inbred strains; congenic strains; recombinant inbred
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