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- 克隆性:
BNI3
- 标记物:
APC
- 规格:
25 tests
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文献和实验Human CD4+CD25highCD127low/neg Regulatory T Cells
CD4+CD25high CD127low/neg regulatory T cells (Tregs) play a critical role in the maintenance of peripheral tolerance and in controlling the development of autoimmune diseases. A combination of surface and intracellular markers, namely, CD25
Polyclonal Expansion of Human CD4+CD25+ Regulatory T Cells
for the efficient in vitro expansion of human Treg cells and identified CD4+ CD25high CD45RA+ T cells as the ideal starting population for the generation of homogeneous and stable Treg cell products. Here, we provide detailed instructions for their identification
of functional tests for the analysis of their suppressive properties, since no specific markers for CD4+ CD25+ T regulatory cells are known so far. In this chapter, techniques applying immunomagnetic beads have been used to establish an efficient method
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