Anti-Human CD2 APC (25 tests)

Human Spongiform Encephalopathy: Clinical Presentation and Diagnostic Tests

The spectrum of human transmissible spongiform encephalopathies, or prion diseases, include sporadic Creutzfeldt-Jakob disease (CJD), familial CJD, iatrogenic CJD, and kuru. Although the disorders are rare and currently untreatable

Laboratory Tests for the Antiphospholipid Syndrome

), anticardiolipin (aCL) antibody, and/or anti‐β2 glycoprotein I (aβ2 GPI) antibody assays. These aPL, considered to be diagnostic markers and pathogenic drivers of APS, are a heterogeneous group of antibodies directed against anionic phospholipids, phospholipid

CD2白细胞分化抗原及其功能

具有进化上的保守性和交叉反应性，如人CD2可与羊红细胞CD58结合，形成羊红细胞(E)花环。CD2分子胞质区两个富含脯氨酸的区域是与Lck激酶分子SH3结构域结合的部位。       CD2与配体结合以及CD2分子所介导的信号转导，不仅增强T细胞与APC或靶细胞之间的黏附，并促进T细胞对抗原的识别和激活。CD2阳性胸腺细胞可与LFA-3阳性的胸腺上皮细胞结合，可能为早期胸腺细胞的活化和分化提供信号。