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- 英文名：
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- 库存：
现货库存
- 供应商：
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- 肿瘤类型：
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- 细胞类型：
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- 品系：
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- 组织来源：
ATCC/DSMZ/ECACC
- 相关疾病：
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- 物种来源：
人或动物
- 免疫类型：
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- 细胞形态：
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- 是否是肿瘤细胞：
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- 器官来源：
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- 运输方式：
常温或干冰
- 年限：
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- 生长状态：
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- 规格：
T25
| 种属 | 大鼠 |
| 组织来源 | 正常鼓膜组织 |
| 传代比例 | 1:2传代 |
| 完全培养基配置 | 基础培养基500ml ；生长添加剂5ml ；双抗5ml |
| 简介 | 鼓膜也称耳膜 ，为一弹性灰白色半透明薄膜 ，将外耳道与中耳隔开。鼓膜穿孔不能愈合 ，可能与干细胞受损或增殖抑 制有关。鼓膜上皮干细胞的分布与鼓膜的血供丰富的区域一致 ，鼓膜上皮干细胞高表达β1整合素 ，有很强的黏附型 ， 对Ⅳ型胶原的黏附鼻其他细胞更快、更强。 |
| 形态 | 铺路石状细胞样 ，不规则细胞样 |
| 生长特征 | 贴壁生长 |
| 细胞检测 | 广谱角蛋白(PCK)免疫荧光染色为阳性免疫荧光鉴定 ，细胞纯度可达90%以上 ，不含有HIV-1、HBV、HCV、支原 体、细菌、酵母和真菌等。 |
remission, even in advanced stages, we engineered RT-MPs with diklerent cytokine and chemokine combinations by modifying their production lkthod. After comparing the therapeutic eklect of the engineered RT-MPs in vitro and in vivo, we demonstrated that tIL-15/tCCL19-RT-MPs eklectively activated anti-tumor immune responses, significantly
important players in the tumor microenvironment. They can directly accelerate malignant cell migration and the formation of metastases. Better understanding of the neuroimmune circuits in the tumor milieu will be instrumental in the development of novel therapeutic approaches for the malignancies known to be associated with inflammation and dysregulated immune
Background: Bone metastases cause morbidity and mortality in multiple malignancies. In addition to portending a dire prognosis, bone metastases cause bone pain, fractures, hypercalcemia, spinal cord compression, and other nerve compression syndromes. Improved understanding of the mechanisms that predispose tumor metastases to bone is needed to improve patients therapeutic options, maintain their quality of life, and improve their survival.
Methods: This review discusses selected preclinical and clinical data regarding bone metastasis development and cytokine/molecular interactions predisposing to bone metastases formation. Potential interventions for reducing bone metastases are also described.
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文献和实验remission, even in advanced stages, we engineered RT-MPs with diklerent cytokine and chemokine combinations by modifying their production lkthod. After comparing the therapeutic eklect of the engineered RT-MPs in vitro and in vivo, we demonstrated that tIL-15/tCCL19-RT-MPs eklectively activated anti-tumor immune responses, significantly
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