- ￥5460
- 南京万木春生物
- 进口/国产
- WM-24JY592
- 2026年04月20日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 英文名：
/
- 库存：
现货库存
- 供应商：
/
- 肿瘤类型：
/
- 细胞类型：
/
- 品系：
/
- 组织来源：
ATCC/DSMZ/ECACC
- 相关疾病：
/
- 物种来源：
人或动物
- 免疫类型：
/
- 细胞形态：
/
- 是否是肿瘤细胞：
/
- 器官来源：
/
- 运输方式：
常温或干冰
- 年限：
/
- 生长状态：
/
| 种属 | 小鼠 |
| 组织来源 | 正常骨髓组织 |
| 传代比例 | 1:2传代 |
| 完全培养基配置 | 基础培养基500ml ；生长添加剂5ml ；胎牛血清50ml ；双抗5ml |
| 简介 | 巨噬细胞源自单核细胞 ，属于免疫细胞 ，有多种功能 ，属不繁殖细胞群 ，难以长期培养 ，巨噬细胞在吞噬和清除异物 和衰老死亡细胞、分泌生物活性物质 ，调节血细胞生成与参与免疫应答等方面发挥着广泛的生物学作用 ，是一类在体 内发挥重要免疫效应的细胞 ，为体内的稳态维持和组织防御提供保障。 |
of tumorigenesis. However, we still do not fully understand why tumors can be contained but not eliminated by the immune system and whether rare CSCs are required for tumor propagation. Long latency or recurrence periods have been described for most tumors. Conceptually, this microenvironment which allows their selective survival over the others. Persistence of Tregs in the tumor microenvironment and suwdtquent immunosuppression makes Tregs a potential therapeutic obstacle and the reason behind the failure of immunotherapy. In this review,
Bone is the most frequent site of breast cancer and prostate cancer metastasis, and one of the most common sites of metastasis for many solid tumors. Once cancer cells colonize in the bone, it imposes a major clinical challenge for the treatment of the disease, and fatality rates increase drastically. Bone, the largest organ in the body, provides a fertile microenvironment enriched with nutrients, growth factors and hormones, a generous reward for cancer cells. Dependent on cancer type, cancer cells can cause osteoblastic (bone forming) or osteolytic lesions to promote the net resorption and/or release of growth factors from the bone extracellular matrix. These processes activate a 'vicious cycle', leading to disruption of bone integrity and promoting cancer cell growth and migration. Cancer cells influence the bone microenvironment favoring their colonization and growth. In order to metastasize to the bone, cancer cells must first migrate from the site of origin, and once established within the bone, they must overcome the dormant inducing effects of resident cells. If successful, cancer cells can then colonize and continually disrupt bone homeostasis that is primarily maintained by osteocytes, the most abundant bone cell type. For example, it has been shown that exercise induces osteocytes to release anabolic factors that inhibit osteoclast resorptive activity, promote dormancy and the release of anti-cancer factors that inhibit breast cancer cell metastasis. In this review, we will summarize recent research findings and provide mechanistic insights related to the role of osteocytes in osteolytic metastasis.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验 specialized niches. Thus, latent tumors may be maintained by a niche-constrained reservoir of long-living CSCs that are exempt from immunosurveillance while niche-independent and more immunogenic daughter cells are constantly eliminated. The small subpopulation of CSCs is often
小鼠骨髓单细胞悬液制备流程 颈椎脱臼法处死小鼠，放在75%酒精中浸泡5 min。提前于超净台上准备一个消毒托盘（可用无菌口罩或者用浸满酒精的纱布代替），取出小鼠并铺于消毒托盘上。 在无菌环境下取小鼠的后肢骨。用眼科镊小心捏起小鼠两髋关节之间的腹部皮肤，用眼科剪小心剪开，并分离两下肢的皮肤。将皮肤往下在脚踝处剪断，往上在髋关节处剪断，游离出小鼠的两条后肢。 小心剥离肌肉（肌肉两端的白色坚韧组织为肌腱，可以顺着肌腱分离，肌肉主要靠肌腱与关节相连），分别剪下Femurs（股骨）和Tibias（胫骨
免疫活性细胞之一。几乎遍布于动物体内一切组织，对颗粒状异物和体内衰老细胞等进行捕食、消化的大型变形虫样细胞之总称。血单核细胞（ bloodmonocyte），肺泡巨噬细胞（ alveolar macropha-ge），腹腔巨噬细胞（ peritoneal macrophage），炎症肉芽肿巨噬细胞（ inflammatory granuloma ma-crophage）等是游离巨噬细胞（ free macrophage）。与此相反，枯否氏星形细胞（ von Kupffer’ s cell
Cell I 乳腺癌良好预后的新型生物标志物— FOLR2+巨噬细胞
当前乳腺癌的发病率居所有女性恶性肿瘤首位，根据世界卫生组织国际癌症研究机构（简称 IARC ）发布的《2021 年全球最新癌症负担》数据，全球乳腺癌新增人数达 265 万，已超越肺癌成为“全球第一大癌症”。目前乳腺癌的主要治疗方式有手术治疗、化学药物治疗、放射治疗、内分泌治疗及靶向治疗等，然而这些治疗手段并不能让所有患者都能有效获益，因而创新药物的研发与上市对于提高乳腺癌患者生存期，改变乳腺癌治疗格局具有深远意义。 肿瘤相关巨噬细胞（tumor-associated macrophage
技术资料暂无技术资料 索取技术资料
