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HLA-DO/B Polyclonal Antibody_货

号:E-AB-19991_多克隆抗体
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  • ¥420 - 2365
  • Elabscience已认证
  • E-AB-19991
  • 武汉
  • 2026年05月21日
  • IHC;ELISA
  • Rabbit
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名

      HLA-DO/B Polyclonal Antibody_货号:E-AB-19991_多克隆抗体

    • 抗体英文名

      HLA-DO/B Polyclonal Antibody

    • 靶点

      HLA-DOB

    • 浓度

      5 μL/Test

    • 应用范围

      IHC;ELISA

    • 宿主

      Rabbit

    • 适应物种

      Human

    • 保质期

      12个月

    • 级别

      科研

    • 库存

      99

    • 供应商

      武汉伊莱瑞特生物科技股/份有限公司

    • 标记物

      HRP

    • 克隆性

      Polyclonal

    • 保存条件

      Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    • 形态

      液体

    • 亚型

      IgG

    • 规格

      200μL/120μL/60μL/20μL

    规格:200μL产品价格:¥2365.0
    规格:120μL产品价格:¥1640.0
    规格:60μL产品价格:¥1010.0
    规格:20μL产品价格:¥420.0
    产品名称:HLA-DO/B Polyclonal Antibody
    货号:E-AB-19991
    Verified Samples
    Verified Samples in IHC:Human tonsil
    Dilution
    IHC 1:40-1:200, ELISA 1:5000-1:10000
    Clonality
    Polyclonal
    Isotype
    IgG
    Immunogen
    Synthetic peptide of human HLA-DO/B
    Abbre
    HLA-DO/B
    Synonyms
    HLA-DO/B;HLA class II histocompatibility antigen;DO beta chain;MHC class II antigen DO/B抗体
    Swissprot
    P13765
    Cellular Localization
    Endosome membrane,Lysosome,lysosomal membrane,lysosome,Plasma Membrane,MHC class II protein complex,Other locations:integral component of membrane
    Concentration
    1.26 mg/mL
    Storage
    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
    Buffer
    PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Purification Method
    Antigen aF/FInity purification
    Research Areas
    Immunology
    Conjugation
    Unconjugated
    Background
    HLA-DO/B belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DO/B), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. HLA-DO/B (Major Histocompatibility Complex, Class II, DO Beta) is a Protein Coding gene. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and CTLA4 Signaling. GO annotations related to this gene include MHC class II protein complex binding and MHC class II receptor activity. An important paralog of this gene is HLA-DRB1.
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    图标文献和实验
    该产品被引用文献
    Elabscience®自创立起,一直秉承自主研发、稳扎稳打、坚持创新、追求卓越的宗旨,为生命科学研究领域的广大学者们提供精细可靠、严格质控的科研产品,包括ELISA试剂盒、抗体、流式抗体、蛋白、代谢检测试剂盒等产品。经过多年来的努力与坚持,我们的产品已经协助发表了超30,967篇SCI文献,其中包括行业期刊 Nature Medicine, Nature, Cell, Immunity, Molecular Cancer, Circulation, Advanced Materials等。
    相关实验
    • Polyclonal and Monoclonal Antibodies

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    • Construction of Polyclonal Antibody Libraries Using Phage Display

      Polyclonal antibody libraries (PCALs) are standardized mixtures of antibodies (Abs) specific for an antigen (Ag) or multi-Ag target (a poly-Ag). As the immunoglobulin (Ig) genes are cloned, the mixtures can be perpetuated, amplified

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    文献支持
    HLA-DO/B Polyclonal Antibody_货号:E-AB-19991_多克隆抗体
    ¥420 - 2365