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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
STRADA Polyclonal Antibody_货号:E-AB-52195_多克隆抗体
- 抗体英文名:
STRADA Polyclonal Antibody
- 应用范围:
IHC;ELISA
- 宿主:
Rabbit
- 适应物种:
Human; Mouse; Rat
- 保质期:
12个月
- 目录编号:
E-AB-52195
- 级别:
科研级别
- 库存:
999
- 供应商:
武汉伊莱瑞特生物科技股份有限公司
- 标记物:
Unconjugated
- 克隆性:
Polyclonal
- 保存条件:
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- 形态:
液体
- 亚型:
IgG
- 规格:
200μL/120μL/60μL/20μL
| 规格: | 200μL | 产品价格: | ¥2365.0 |
|---|---|---|---|
| 规格: | 120μL | 产品价格: | ¥1640.0 |
| 规格: | 60μL | 产品价格: | ¥1010.0 |
| 规格: | 20μL | 产品价格: | ¥420.0 |
货号:E-AB-52195
| Verified Samples |
Verified Samples in IHC:Human colorectal cancer,Human tonsil
|
| Dilution |
IHC 1:45-1:300, ELISA 1:5000-1:10000
|
| Clonality |
Polyclonal
|
| Isotype |
IgG
|
| Immunogen |
Full length fusion protein
|
| Abbre |
STRADA
|
| Synonyms |
Protein kinase LYK5;Serologically defined breast cancer antigen NY BR 96;STE20 related adapter protein;STRAD alpha;STRAD抗体
|
| Swissprot |
Q7RTN6
|
| Cellular Localization |
Cytoplasmic and Nuclear
|
| Concentration |
1.5 mg/mL
|
| Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
| Buffer |
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
|
| Purification Method |
Antigen affinity purification
|
| Research Areas |
Cancer; Cell Biology; Metabolism; Immunology
|
| Conjugation |
Unconjugated
|
| Background |
The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known.
|
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