PLAUR 多克隆抗体

Western Blot（WB）已验证样本:A549
免疫组织化学（IHC）已验证样本:Human lung cancer,Human colon cancer

WB 1:500-1:2000, IHC 1:50-1:200

Polyclonal

IgG

Recombinant protein of human PLAUR

PLAUR

CD 87;CD87;CD87 antigen;MO 3;MO3;Monocyte activation antigen Mo3;Plasminogen activator receptor urokinase;Plasminogen activator urokinase receptor;PLAUR;U PAR;u plasminogen activator receptor;U-PAR;u-plasminogen activator receptor form 2;UPA receptor;uPAR;UPAR;Urinary plasminogen activator receptor;URKR;Urokinase plasminogen activator receptor;Urokinase plasminogen activator surface receptor;urokinase-type plasminogen activator (uPA) receptor抗体

Q03405

37kDa

Secreted and Cell membrane.

0.2 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Cancer; Cardiovascular; Immunology

Unconjugated

This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.