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文献和实验【on-target2.0】AAV感染胰腺 | 血清型·启动子·注射用量 | 一篇就GO了!
参考文献(向上滑动) [1] Röder PV, Wu B, Liu Y, Han W. Pancreatic regulation of glucose homeostasis. Exp Mol Med. 2016;48(3):e219. [2] Wang YC, Mao XT, Sun C, et al. Pancreas-directed AAV8-hSPINK1 gene therapy safely and effectively protects
Assay of superoxide dismutase activity
. The reaction of SOD is as follows: 2H+ + 2 •O2_ ® H2O2 + O2 the produced hydrogen peroxide is then detoxified by catalase or peroxidase. The expression of SOD genes is regulated both spatially and developmentally at least in maize (Zhu and Scandalios
α signaling (5 ). Regulation of SOCS protein translation by interferon-regulated microRNAs (IRmiRs) would enhance the potential of cytokine fine regulation. It has been reported that miR-19 antagonists lead to higher SOCS1 levels and miR-19 mimics can repress
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