PARP11 inhibitor ITK7,2411890-

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PARP11 inhibitor ITK7

CAS No. : 2411890-36-1

MCE 国际站：PARP11 inhibitor ITK7

产品活性：PARP11 inhibitor ITK7 (ITK7) 是一种有效的选择性 PARP11 抑制剂。PARP11 inhibitor ITK7 可有效抑制 PARP11，IC₅₀ 值为 14 nM。PARP11 inhibitor ITK7 可用于细胞定位的研究。

研究领域：Cell Cycle/DNA Damage  |  Epigenetics

作用靶点：PARP

In Vitro: PARP11 inhibitor ITK7 (ITK7) can potently inhibit PARP11 with an IC₅₀ value of 14 nM.
ITK7 exhibits a dose-dependent inhibition of PARP11-dependent auto-MARylation with an EC₅₀ value of 13 nM.
ITK7 (0, 0.03, 0.1, 0.3, 1, 3 μM; 3 h) inhibits PARP11 auto-MARylation activity in cells and causes PARP11 to dissociate from the nuclearenvelope.

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