- ￥1240
- SIGMA
- 美国
- 60615-5g
- 2025年07月07日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
瓶身
- 保质期：
coa
- 英文名：
SIGMA
- 库存：
999
- 供应商：
麦飞生物
- CAS号：
70560-51-9
- 规格：
60615-5g
说明
一般描述
Chemical structure: aminoglycoside
应用
Kanamycin sulfate is a broad spectrum aminoglycoside-antibiotic derived from Streptomyces kanamyceticus. It is used as an additive in culture media for the isolation of group D streptococci on Kanamycin Esculin Azide Agar and for selection of transformed plant cells containing the neomycin phosphotransferase on a kanamycin-medium.†† Kanamycin sulfate can also be used as a selection agent for cells transformed with kanamycin B resistance gene. It is recommended for use in cell culture applications at 100 μg/mL.
生化/生理作用
Mode of Action: The product acts by binding to the 70S ribosomal subunit, inhibiting translocation and eliciting miscoding.
Mode of Resistance: Aminoglycoside-modifying enzymes (including acetyltransferase, phosphotransferase, nucleotidyltransferase) can alter this antibiotic, preventing its interaction with ribosomes.
Antimicrobial Spectrum: Kanamycin sulfate is effective against gram-negative and gram-postiive bacteria, and mycoplasma.
包装
5g, 25 g
注意
Solutions are stable at 37°C for approximately 5 days. Aqueous stock solutions can be stored at 2-8°C for long term storage.
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文献和实验Cryptic genetic variation accelerates evolution by opening access to diverse adaptive peaks.
Jia Zheng et al.
Science (New York, N.Y.), 365(6451), 347-353 (2019-07-28)
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