Cyanine7 抗小鼠/人 KLRG1 (MAFA) 荧光

Cyanine7 anti-mouse/human KLRG1 (MAFA) Antibody-PE详细如下：

Description ：Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell functionassociated antigen (MAFA or 2F1-Ag). KLRG1 is a type II membrane glycoprotein that wasfirst identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer ofglycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed bysubsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 isalso expressed on subsets of CD8 and CD4 cells, including CD4 and CD8 effector/memorycells, potent regulatory CD4 T cells. KLRG1 may be involved in regulating NK cellhomeostasis. KLRG1 was found to recognize cadherins and thus inhibit immune responses byregulating the effector function and the developmental processes of NK and T cells.

Verified Reactivity ：Mouse, Human

Antibody Type ：Monoclonal

Host Species ：Syrian Hamster

Immunogen ：IL-2 activated NK cells from C57BL/6 mice

Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation ：The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 underoptimal conditions.

Concentration ：0.2 mg/ml

Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.

Application ：FC - Quality tested

Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is =0.5 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.

Excitation Laser ：Blue Laser (488 nm)、Green Laser (532 nm)、Yellow-Green Laser (561 nm)