抗人 CD270 (HVEM, TR2) 荧光标记PE 抗体

anti-human CD270 (HVEM, TR2) Antibody-PE详细如下：

Description ：The 122 antibody recognizes human HVEM also known as herpesvirus entry mediator A, tumornecrosis factor receptor superfamily, member 14, TNFRSF14, and tumor necrosis factorreceptor like 2. HVEM, a member of the TNFR superfamily, is a type I transmembrane proteincontaining 2 TNF receptor domains with a predicted molecular weight of approximately 30 kD.HVEM is widely expressed in blood vessels, brain, heart, kidney, liver, lung, prostate, spleen,thymus and other organs. Resting T cells and naïve and memory B cells express high levels ofHVEM as well. In humans, HVEM is not expressed in germinal center B cells. Immature dendriticcells express high levels of HVEM that is downregulated upon maturation. HVEM plays animportant role in herpes simplex virus pathogenesis by enhancing entry into cells. Signalingthrough HVEM activates JNK1, NF-κB and AP-1 to control gene expression in response toinfection or cellular stress and activate the immune response. HVEM binds to LIGHT and hasalso been shown to associate with several other proteins including TRAF1, TRAF2, TRAF3,TRAF5, B and T lymphocyte associated protein (BTLA), and estrogen receptor alpha.

Verified Reactivity ：Human

Reported Reactivity ：African Green, Baboon, Cynomolgus, Rhesus

Antibody Type ：Monoclonal

Host Species ：Mouse

Immunogen ：Recombinant human HVEM protein

Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation ：The antibody was purified by affinity chromatography, and conjugated with PE under optimalconditions.

Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)

Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.

Application ：FC - Quality tested

Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser ：Blue Laser (488 nm)、Green Laser (532 nm)、Yellow-Green Laser (561 nm