ATF2 (phospho Ser 490 / 498)

ATF2 (phospho Ser 490 / 498) 抗体，ATF2 (phospho Ser 490 / 498) Antibody，ATF2 (phospho Ser 490 / 498) 抗体,ATF2 (phospho Ser 490 / 498) Antibody

产品名称：ATF2 (phospho Ser 490 / 498) 抗体-ATF2 (phospho Ser 490 / 498) Antibody

产品货号：PSI-XPS-1002-0.1mL

产品规格：0.1mL

背景资料：The activating transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 has been implicated in the transcriptional regulation of a number of genes including cytokines, cell cycle control and apoptosis. Various forms of cellular stress, including inflammatory cytokines and UV irradiation, stimulate the transcriptional activity of ATF-2. Stress induced ATF-dependent transcription is dependent on phosphorylation of ATF. Serine 490 and serine 498 are novel phosphorylation sites on ATF that have recently been identified. In addition, ATF2 is particularly abundant in the brain and the ATF2 family of transcription factors is considered important substrates of signals upstream of the activation of genes associated with neuronal growth and differentiation. ATF expression has also been linked to the depression in humans.

保存建议：ATF2 (phospho Ser 490 / 498) 抗体-ATF2 (phospho Ser 490 / 498) Antibody taken without freeze/thawing due to the presence of 50% glycerol

应用类型：WB, IHC

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