CD8a 抗体 [53-6.7] (APC-Cy5.5)-C

CD8a 抗体 [53-6.7] (APC-Cy5.5)，CD8a Antibody [53-6.7] (APC-Cy5.5)，CD8a 抗体 [53-6.7] (APC-Cy5.5),CD8a Antibody [53-6.7] (APC-Cy5.5)

产品名称：CD8a 抗体 [53-6.7] (APC-Cy5.5)-CD8a Antibody [53-6.7] (APC-Cy5.5)

产品货号：PSI-98-624-0.1mg

产品规格：0.1mg

背景资料：In the mouse, CD8 exists in two forms – (i) a CD8 heterodimer composed of an alpha chain (CD8alpha) and a beta chain (CD8beta); and (ii) a homodimer of two alpha chains. The heterodimer is found on the surface of essentially all thymocytes and the “suppressor/cytotoxic” subpopulation of mature T lymphocytes. Subsets of intestinal intraepithelial lymphocytes express CD8alpha without CD8beta. It has been suggested that CD8+beta- T cells mature extrathymically, while development of the CD8alpha+beta+ population of T cells is thymus-dependent. CD8 acts as a coreceptor with MHC Class I-restricted T cell receptors in antigen recognition and positive selection of MHC class I-restricted CD8+ T cells. In vivo and in vitro treatment with the 53-6.7 monoclonal antibody effectively depletes CD8alpha+ cells. The 53-6.7 monoclonal antibody also blocks allogeneic help specific for class I MHC antigens and T cell responses to IL-2.

保存建议：CD8a 抗体 [53-6.7] (APC-Cy5.5)-CD8a Antibody [53-6.7] (APC-Cy5.5)Store vial at 2-8℃

应用类型：E, WB, IP

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