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- ProSci
- 美国
- PSI-98-773-0.5mg
- 2025年07月11日
- WB, IHC-P, IHC-Fr, ICC, Flow, IP, Adhesion
- 仓鼠
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Activated mouse Th1 clone D1.6
- 保存条件：
Store vial at -20℃
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
仓鼠
- 应用范围：
WB, IHC-P, IHC-Fr, ICC, Flow, IP, Adhesion
- 抗体英文名：
CD154 Antibody [MR1]
- 抗体名：
CD154 Antibody [MR1]
- 规格：
0.5mg
【干冰】CD154 抗体 [MR1]，CD154 Antibody [MR1]，【干冰】CD154 抗体 [MR1],CD154 Antibody [MR1]
产品名称：【干冰】CD154 抗体 [MR1]-CD154 Antibody [MR1]
产品货号：PSI-98-773-0.5mg
产品规格：0.5mg
背景资料：CD154, formerly known as CD40 ligand and gp39, is a type II integral membrane protein and a member of the tumor necrosis factor (TNF) family of ligands. It is an important accessory molecule in T cell-B cell costimulatory interactions and is expressed predominantly on activated CD4+ T lymphocytes. It is also present on the surface of activated Th0, Th1, and Th2 T cell clones. Its expression is transient and cyclosporin-sensitive. The MR1 monoclonal antibody binds to murine CD154 with high affinity, blocks binding to CD40, and blocks CD154 function. Administration of this antibody to mice blocks the ability to mount primary and secondary immune responses to TD antigens yet does not alter the immune response to TI antigens.
保存建议：【干冰】CD154 抗体 [MR1]-CD154 Antibody [MR1]Store vial at -20℃
应用类型：WB, IHC-P, IHC-Fr, ICC, Flow, IP, Adhesion
点击：【干冰】CD154 抗体 [MR1]-CD154 Antibody [MR1]查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验IT同 不使用IT的疗法之间每多大的区别（SJ，Knechtle，unpublished data）。从机械的观点看，我们认为IT更容易引起早期的T细胞活化，而不是细胞死亡。当用IT两周后，IT在延长器官的存活期限方面，主要同T细胞的排除程度有关（T cell depletion）。（SJ，Knechtle，unpublished data）。 抗CD154抗体治疗（Anti-CD154 therapy）： CD154—又称为CD40受体，、ly-62和gp39，是一条分子量为36Kda的糖
protocols involving costimulation blockade have recently been developed. The prototypical murine protocol described in this chapter, involves the use of CTLA4Ig and a monoclonal antibody-specific for CD154 (CD40L) for costimulation blockade, 3 Gy
Multiparameter Intracellular Cytokine Staining
, such as upregulation of CD107 or CD154, as well as phenotypic markers that define specific cellular subsets, e.g. effector and memory T-cell compartments. Recent advances in multicolor flow cytometry instrumentation and software have allowed the routine combination
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