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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Cyclin D1 (phospho Thr286) antibody was raised against a peptide sequence around phosphorylation site of threonine 286 (A-C-T (p)-P-T) derived from Human Cyclin D1.
- 保存条件:
Store antibody at -20℃ for up to one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
WB
- 抗体英文名:
Cyclin D1 (phospho Thr286) Antibody
- 抗体名:
Cyclin D1 (phospho Thr286) Antibody
- 规格:
0.1mg
Cyclin D1 (phospho Thr286) 抗体,Cyclin D1 (phospho Thr286) Antibody,Cyclin D1 (phospho Thr286) 抗体,Cyclin D1 (phospho Thr286) Antibody
产品名称:Cyclin D1 (phospho Thr286) 抗体-Cyclin D1 (phospho Thr286) Antibody
产品货号:PSI-80-017-0.1mg
产品规格:0.1mg
背景资料:Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1. Ubiquitinates STUB1-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.
保存建议:Cyclin D1 (phospho Thr286) 抗体-Cyclin D1 (phospho Thr286) AntibodyStore antibody at -20℃ for up to one year
应用类型:WB
点击:Cyclin D1 (phospho Thr286) 抗体-Cyclin D1 (phospho Thr286) Antibody查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验Immunodetection of cyclin D1 and D2/D3 using flow cytometry
. It has been tested with antibodies against cyclin D1 (Pharmingen cat. no. 14561A, clone G12-4326), cyclin D2/D3 (cat. no. 14711A, clone G107-22) and cyclin E Procedure Prepare the cell type of interest as a single cell suspension and wash once with cold PBS
Disorders of the cell cycle regulatory machinery play a key role in the pathogenesis of cancer. The gene encoding the cyclin D1 protein, a regulator of the progression from the G1- to S-phase, is often found disrupted in the cancer cell
Immunodetection of cyclin D1 and D2/D3 using 488/630 nm dual laser flow cytometr(图)
. It has been tested with antibodies against cyclin D1 (Pharmingen cat. no. 14561A, clone G12-4326), cyclin D2/D3 (cat. no. 14711A, clone G107-22) and cyclin E, and is based on protocols originally designed by Z. Darzynkiewicz and colleagues. Although FITC-conjugated
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