Androgen Receptor (phospho Tyr

Androgen Receptor (phospho Tyr363) 抗体，Androgen Receptor (phospho Tyr363) Antibody，Androgen Receptor (phospho Tyr363) 抗体,Androgen Receptor (phospho Tyr363) Antibody

产品名称：Androgen Receptor (phospho Tyr363) 抗体-Androgen Receptor (phospho Tyr363) Antibody

产品货号：PSI-79-872-0.1mg

产品规格：0.1mg

背景资料：The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described.

保存建议：Androgen Receptor (phospho Tyr363) 抗体-Androgen Receptor (phospho Tyr363) AntibodyStore antibody at -20℃ for up to one year

应用类型：WB

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