- ￥22
- ProSci
- 美国
- PSI-63-483-400ul
- 2025年07月13日
- WB, IHC-P
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
This CTDSP1-V250 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-261 amino acids from the C-terminal region of human CTDSP1-V250.
- 保存条件：
Store at 4℃ for three months and -20℃, stable for up to one year
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
WB, IHC-P
- 抗体英文名：
CTDSP1-V250 Antibody
- 抗体名：
CTDSP1-V250 Antibody
- 规格：
400ul
CTDSP1-V250 抗体，CTDSP1-V250 Antibody，CTDSP1-V250 抗体,CTDSP1-V250 Antibody
产品名称：CTDSP1-V250 抗体-CTDSP1-V250 Antibody
产品货号：PSI-63-483-400ul
产品规格：400ul
背景资料：CTDSP1 is a class 2C phosphatase with activity dependent on the conserved DxD motif. Expression of CTDSP1 inhibited activated transcription from several promoter-reporter gene constructs, but expression of a mutant lacking phosphatase activity enhanced transcription. Neuronal gene transcription is repressed in nonneuronal cells by the repressor element-1 (RE1)-silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF; 600571) complex. REST/NRSF recruits SCPs to neuronal genes that contain RE1 elements, leading to neuronal gene silencing in nonneuronal cells. Phosphatase-inactive forms of SCP interfere with REST/NRSF function and promote neuronal differentiation of P19 stem cells. Likewise, small interfering RNA directed to the single Drosophila SCP unmasks neuronal gene expression in S2 cells. Thus, SCP activity is an evolutionarily conserved transcriptional regulator that acts globally to silence neuronal genes.
保存建议：CTDSP1-V250 抗体-CTDSP1-V250 AntibodyStore at 4℃ for three months and -20℃, stable for up to one year
应用类型：WB, IHC-P
点击：CTDSP1-V250 抗体-CTDSP1-V250 Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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