Metabotropic Glutamate Recepto

Metabotropic Glutamate Receptor 7 抗体，Metabotropic Glutamate Receptor 7 Antibody，Metabotropic Glutamate Receptor 7 抗体,Metabotropic Glutamate Receptor 7 Antibody

产品名称：Metabotropic Glutamate Receptor 7 抗体-Metabotropic Glutamate Receptor 7 Antibody

产品货号：PSI-58-462-400ul

产品规格：400ul

背景资料：L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternative splice variants of GRM8 have been described but their full-length nature has not been determined.

保存建议：Metabotropic Glutamate Receptor 7 抗体-Metabotropic Glutamate Receptor 7 AntibodyStore at 4℃ for three months and -20℃, stable for up to one year

应用类型：WB, IHC-P

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