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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Produced from sera of rabbits immunized with highly pure recombinant Human EGF Receptor. Human EGF Receptor specific antibody was purified by affinity chromatography employing an immobilized Human EGF Receptor matrix.
- 保存条件:
The lyophilized antibody is stable for at least 2 years from date of receipt at -20℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
E, WB
- 抗体英文名:
EGF Receptor Antibody
- 抗体名:
EGF Receptor Antibody
- 规格:
0.1mg
EGF Receptor 抗体,EGF Receptor Antibody,EGF Receptor 抗体,EGF Receptor Antibody
产品名称:EGF Receptor 抗体-EGF Receptor Antibody
产品货号:PSI-38-264-0.1mg
产品规格:0.1mg
背景资料:
保存建议:EGF Receptor 抗体-EGF Receptor AntibodyThe lyophilized antibody is stable for at least 2 years from date of receipt at -20℃
应用类型:E, WB
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文献和实验EGF受体是一种糖蛋白, 广泛分布于哺乳动物的上皮细胞、人的成纤维细胞、胶质细胞、角质细胞等。EGF 受体是一条含有1186个氨基酸残基的多肽链, 相对分子质量为170kDa,由三个部分组成:①很大的细胞外结构域:约621个氨基酸残基,富含半胱氨酸(51个), 并形成多对二硫键,其上结合有糖基,是EGF结合的位点。②跨膜区∶由23个氨基酸残基组成;③细胞质结构域,由542个氨基酸残基组成,含有无活性的酪氨酸激酶和几个酪氨酸磷酸化的位点。
Assays to Monitor Degradation of the EGF Receptor
to conduct receptor downregulation assays are described. Monitoring of ubiquitination and degradation of the EGFR subsequent to stimulation with the receptor ligand EGF is described. Finally, protocols to quantitatively measure degradation of the EGFR
Motility Signaled From the EGF Receptor and Related Systems
Cell motility is now recognized as central to many biological processes. Growth factors, such as those that activate the epidermal growth factor receptor (EGFR), drive biochemically and biologically distinct subsets of migration critical
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