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- ProSci
- 美国
- PSI-36-300-50ug
- 2025年07月12日
- E, WB
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human clusterin (nuclear form).
- 保存条件：
Stable for at least 6 months after receipt when stored at -20℃
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
E, WB
- 抗体英文名：
Clusterin Antibody (biotin)
- 抗体名：
Clusterin Antibody (biotin)
- 规格：
50ug
Clusterin 抗体 (biotin)，Clusterin Antibody (biotin)，Clusterin 抗体 (biotin),Clusterin Antibody (biotin)
产品名称：Clusterin 抗体 (biotin)-Clusterin Antibody (biotin)
产品货号：PSI-36-300-50ug
产品规格：50ug
背景资料：Clusterin shares homology with the small heat shock protein family of molecular chaperones. The mature secreted form of the protein is a glycosylated, 80-kDa disulfide-linked heterodimer of alpha and beta subunits (produced by internal cleavage). Clusterin is expressed in virtually all tissues and found in all human fluids. It is involved in numerous physiological processes important for carcinogenesis and tumor growth, including apoptotic cell death, cell cycle regulation, DNA repair, cell adhesion, tissue remodeling, lipid transportation, membrane recycling, and immune system regulation. Clusterin also exists as a nuclear protein. The secreted form of Clusterin has extracellular chaperone and anti-apoptotic activities while the nuclear form acts as a proapoptotic factor.
保存建议：Clusterin 抗体 (biotin)-Clusterin Antibody (biotin)Stable for at least 6 months after receipt when stored at -20℃
应用类型：E, WB
点击：Clusterin 抗体 (biotin)-Clusterin Antibody (biotin)查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验The Avidin-Biotin Complex (ABC) Method and Other Avidin-Biotin Binding Methods
These methods involve, at their core, the vitamin biotin and the protein avidin, which bind together irreversibly. By establishing a biotin link, through avidin, between the horseradish peroxidase enzyme and a secondary antibody reagent
The Avidin-Biotin Complex(ABC) Method
, between the horseradish peroxidase enzyme and a secondary antibody reagent, enzyme localization can be achieved at the site of primary antibody interaction with the specimen (see ) Fig. 1 ). The biotin molecule is small and can be easily conjugated to immunoglobulin
Identification of Deacetylase Substrates with the Biotin Switch Approach
The identification of lysine-acetylated proteins and deacetylase substrates has primarily relied on protein immune-affinity techniques with antibodies that recognize acetylated lysine residues (Kac antibodies). While these antibody-based
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