TNF-alpha 抗体 [SPM543]-TNF-alph

TNF-alpha 抗体 [SPM543]，TNF-alpha Antibody [SPM543]，TNF-alpha 抗体 [SPM543],TNF-alpha Antibody [SPM543]

产品名称：TNF-alpha 抗体 [SPM543]-TNF-alpha Antibody [SPM543]

产品货号：PSI-34-172-100ug

产品规格：100ug

背景资料：Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17kDa band following SDS PAGE under non-reducing conditions. TNF alpha is closely related to the 25kDa protein Tumor Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.

保存建议：TNF-alpha 抗体 [SPM543]-TNF-alpha Antibody [SPM543]Aliquot and Store at 2-8℃

应用类型：Flow, IF, IHC

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