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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
A cytoskeletal fraction of rat colon epithelium was used as the immunogen for this Cytokeratin 17 antibody.
- 保存条件:
Aliquot and Store at 2-8℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
小鼠
- 应用范围:
Flow, IF, WB, IHC
- 抗体英文名:
Cytokeratin 17 Antibody [SPM560]
- 抗体名:
Cytokeratin 17 Antibody [SPM560]
- 规格:
100ug
Cytokeratin 17 抗体 [SPM560],Cytokeratin 17 Antibody [SPM560],Cytokeratin 17 抗体 [SPM560],Cytokeratin 17 Antibody [SPM560]
产品名称:Cytokeratin 17 抗体 [SPM560]-Cytokeratin 17 Antibody [SPM560]
产品货号:PSI-34-145-100ug
产品规格:100ug
背景资料:Cytokeratin 17 (CK17) is a member of the Cytokeratin subfamily of intermediate filament proteins (IF's). It is unique in that it is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. CK17 is expressed in the nail bed, hair follicle, sebaceous glands and other epidermal appendages. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glands such as mammary, sweat and salivary. CK17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. It may be considered an epithelial stem cell marker because CK17 Ab marks basal cell differentiation. CK17 can be useful when included in a panel of antibodies against TTF-1, napsin A, CK5&6, p63, and SOX-2 for diagnostic differentiation between lung adenocarcinoma (LADC) and lung squamous cell carcinoma (SCLC), especially for poorly-differentiated lung carcinoma. CK17 is expressed in SCLC much higher than in LADC. In breast carcinomas, approximately 20% of patients show no expression of ER, PR and Her2, which are defined as triple negative tumor. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course. The histologic differentiation of ampullary cancer, intestinal vs. pancreatobiliary, is very important for treatment. Usually anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype.
保存建议:Cytokeratin 17 抗体 [SPM560]-Cytokeratin 17 Antibody [SPM560]Aliquot and Store at 2-8℃
应用类型:Flow, IF, WB, IHC
点击:Cytokeratin 17 抗体 [SPM560]-Cytokeratin 17 Antibody [SPM560]查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验整个抗体市场的信任危机,早在多年前就未雨绸缪,展开了一些列对于抗体特异性的探索和研发- UltraMAB® 超高特异性抗体就应运而生。OriGene UltraMAB® 超高特异性抗体采用独特的 17k 蛋白芯片验证,OriGene 高密度蛋白芯片上包含 17,000 个 HEK293T 细胞蛋白过表达裂解物,每种蛋白裂解液在芯片上具有两个拷贝的重复。蛋白裂解液被印迹在硝酸纤维素膜上。每一钟蛋白裂解液的定位可以通过 Excel 文件进行准确定位。蛋白芯片上蛋白分为 40 个亚矩阵,每个亚矩阵上有
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 大鼠白介素 -17(IL-17)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗大鼠 IL-17 单抗包被于酶标板上,标准品和样品中的 IL-17 与单抗结合,加入生物素化的抗大鼠 IL-17 ,形成免疫复合物连接
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 豚鼠白介素-17 (IL- 17 )ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗豚鼠 IL-17 单抗包被于酶标板上,标准品和样品中的 IL-17与单抗结合,加入生物
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