EMI-1 抗体 [FBXP5]-EMI-1 Antibod

EMI-1 抗体 [FBXP5]，EMI-1 Antibody [FBXP5]，EMI-1 抗体 [FBXP5],EMI-1 Antibody [FBXP5]

产品名称：EMI-1 抗体 [FBXP5]-EMI-1 Antibody [FBXP5]

产品货号：PSI-33-932-100ug

产品规格：100ug

背景资料：Early Mitotic Inhibitor-1 regulates mitosis by inhibiting the anaphase promoting complex/cyclosome (APC). It is a conserved F box protein containing a zinc-binding region essential for APC inhibition. The protein functions to promote cyclin A accumulation and S phase entry in somatic cells by inhibiting the APC complex. At the G1-S transition, EMI-1 is transcriptionally induced by the E2F transcription factor. Overexpression accelerates S-phase entry and can override a G1 block caused by overexpression of Cdh1 or the E2F-inhibitor p105 retinoblastoma protein (pRb). Depleting cells of EMI-1 through RNA interference prevents accumulation of cyclin A and inhibits S phase entry.

保存建议：EMI-1 抗体 [FBXP5]-EMI-1 Antibody [FBXP5]Aliquot and Store at 2-8℃

应用类型：WB, IF, IHC-P

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