- ￥22
- ProSci
- 美国
- PSI-33-787-100ug
- 2025年07月13日
- IF, IHC-P
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A recombinant partial protein corresponding to amino acids 258-385 from the human protein was used as the immunogen for this recombinant CFTR antibody.
- 保存条件：
Aliquot and Store at 2-8℃
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
IF, IHC-P
- 抗体英文名：
Recombinant CFTR Antibody [CFTR/1775R]
- 抗体名：
Recombinant CFTR Antibody [CFTR/1775R]
- 规格：
100ug
Recombinant CFTR 抗体 [CFTR/1775R]，Recombinant CFTR Antibody [CFTR/1775R]，Recombinant CFTR 抗体 [CFTR/1775R],Recombinant CFTR Antibody [CFTR/1775R]
产品名称：Recombinant CFTR 抗体 [CFTR/1775R]-Recombinant CFTR Antibody [CFTR/1775R]
产品货号：PSI-33-787-100ug
产品规格：100ug
背景资料：Recognizes a protein of 165-170kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.
保存建议：Recombinant CFTR 抗体 [CFTR/1775R]-Recombinant CFTR Antibody [CFTR/1775R]Aliquot and Store at 2-8℃
应用类型：IF, IHC-P
点击：Recombinant CFTR 抗体 [CFTR/1775R]-Recombinant CFTR Antibody [CFTR/1775R]查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验, other common mutations exist in most populations, each reaching frequencies of approx 1–2%. Examples include the 1717-1G→A, G542X, G551D, R553X, W1282X, and N1303K mutations. Finally, for a given ethnic population, “ethnic-specific” mutation(s) that reach
Reconstitution of CHIP E3 Ubiquitin Ligase Activity
to monitor the folding status of the CFTR protein, and we have successfully reconstituted this activity using a recombinant CFTR fragment consisting of the cytosolic NBD1 and R domains. We have found that efficient ubiquitination of substrates requires
遗传异质性是由于基因变异 ( 其中绝大多数为 SNP) 引起的 遗传 异质性是由于基因变异(其中绝大多数为SNP)引起的，如APOE*E4与老年性痴呆、V因子1691G+A与深静脉血栓形成存在很强的相关性。不同基因的突变与不同的表型相关，但事实上同一基因的突变可能与许多疾病表型相关。例如，ATRX转录因子的不同突变导致不同表型的智力低下。在其他一些情况下，单个基因的突变甚至可以产生毫不相关的多种异常表型。如果携带2个无效CFTR等位基因的患者患严重的囊性
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