Beta Catenin 抗体 [CTNNB1/1509]-

Beta Catenin 抗体 [CTNNB1/1509]，Beta Catenin Antibody [CTNNB1/1509]，Beta Catenin 抗体 [CTNNB1/1509],Beta Catenin Antibody [CTNNB1/1509]

产品名称：Beta Catenin 抗体 [CTNNB1/1509]-Beta Catenin Antibody [CTNNB1/1509]

产品货号：PSI-33-617-100ug

产品规格：100ug

背景资料：Beta-Catenin associates with the cytoplasmic portion of E-Cadherin, which is necessary for the function of E-Cadherin as an adhesion molecule. In normal tissues, beta-Catenin is localized to the membrane of epithelial cells, consistent with its role in the cell adhesion complex. In breast ductal neoplasia, beta-catenin is usually localized in cellular membranes. However, in lobular neoplasia, a marked redistribution of beta-Catenin throughout the cytoplasm results in a diffuse cytoplasmic pattern. Immunostaining of beta-Catenin and E-Cadherin is helps in the accurate identification of ductal and lobular neoplasms, including a distinction between low-grade ductal carcinoma in situ (DCIS) and lobular carcinoma. Additionally, some rectal and gastric adenocarcinomas demonstrate diffuse cytoplasmic beta-catenin staining and a lack of membranous staining, mimicking the staining pattern observed with lobular breast carcinomas.

保存建议：Beta Catenin 抗体 [CTNNB1/1509]-Beta Catenin Antibody [CTNNB1/1509]Aliquot and Store at 2-8℃

应用类型：IHC-P, Flow, IF, WB

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