CLIP 抗体 [CLIP/813]-CLIP Antibo

CLIP 抗体 [CLIP/813]，CLIP Antibody [CLIP/813]，CLIP 抗体 [CLIP/813],CLIP Antibody [CLIP/813]

产品名称：CLIP 抗体 [CLIP/813]-CLIP Antibody [CLIP/813]

产品货号：PSI-33-571-100ug

产品规格：100ug

背景资料：Recognizes proteins of 33, 35 and 41kDa, which are identified as various isoforms of CD74/CLIP. Its epitope is localized in the extracellular domain of CD74. CD74/CLIP is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. The molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74/CLIP is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, and dendritic cells and by various types of carcinomas. It is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74/CLIP stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas and has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).

保存建议：CLIP 抗体 [CLIP/813]-CLIP Antibody [CLIP/813]Aliquot and Store at 2-8℃

应用类型：Flow, IF, IHC

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