Thymidylate Synthase 抗体 [TS106

Thymidylate Synthase 抗体 [TS106]，Thymidylate Synthase Antibody [TS106]，Thymidylate Synthase 抗体 [TS106],Thymidylate Synthase Antibody [TS106]

产品名称：Thymidylate Synthase 抗体 [TS106]-Thymidylate Synthase Antibody [TS106]

产品货号：PSI-33-561-100ug

产品规格：100ug

背景资料：It recognizes a protein of 36kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.

保存建议：Thymidylate Synthase 抗体 [TS106]-Thymidylate Synthase Antibody [TS106]Aliquot and Store at 2-8℃

应用类型：WB, Flow, IF, IHC

点击：Thymidylate Synthase 抗体 [TS106]-Thymidylate Synthase Antibody [TS106]查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。