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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
A recombinant human protein was used as the immunogen for the E-Cadherin antibody.
- 保存条件:
Aliquot and Store at 2-8℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
小鼠
- 应用范围:
Flow, IF, WB, IHC-P
- 抗体英文名:
E-Cadherin Antibody [SPM381]
- 抗体名:
E-Cadherin Antibody [SPM381]
- 规格:
100ug
E-Cadherin 抗体 [SPM381],E-Cadherin Antibody [SPM381],E-Cadherin 抗体 [SPM381],E-Cadherin Antibody [SPM381]
产品名称:E-Cadherin 抗体 [SPM381]-E-Cadherin Antibody [SPM381]
产品货号:PSI-33-685-100ug
产品规格:100ug
背景资料:Recognizes a protein of 80-120kDa, identified as E-cadherin/CDH1. Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as b-catenin, to regulate cadherin function. E-cadherin plays an important role in epithelial cell adhesion. A decreased expression of E-cadherin is associated with metastatic potential and poor prognosis in breast cancer, prostate and esophageal cancer. In combination with p120 Catenin, it is useful for the differentiation between ductal (E-cadherin +) and lobular (E-cadherin -) breast carcinomas. It may also help in diagnosis of mesothelioma.
保存建议:E-Cadherin 抗体 [SPM381]-E-Cadherin Antibody [SPM381]Aliquot and Store at 2-8℃
应用类型:Flow, IF, WB, IHC-P
点击:E-Cadherin 抗体 [SPM381]-E-Cadherin Antibody [SPM381]查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验上皮及间皮类常用标记抗体EPITHELIAL AND MESOTHELIAL MARKERSCK (MNF 116)- MNF-116 is a pan-cytokeratin antibody.- Source: Dakopatts.- Dilution 1:50.- Antigen retrieval method: HIER (pressure cooking) using EDTA.- Staining pattern: Cytoplasmic, typically
, which is prevalent in epithelial tissues. It has been shown to play a crucial role in the process of tumor cell metastasis. If you want to detect E-cadherin only, you should use E-cadherin antibody instead of Pan Cadherin antibody 按他(她)这样说应该一个带pan的抗体就可以检测
。 如果beta-catenin抗体不好使,或者EGFP太大影响定位的话,还可以构建Flag标签类载体,转染细胞,加入药物,用抗Flag抗体免疫荧光检测,荧光显微镜下观察就好了。 wangjh28 但按照事先的推测,处理了以后会下调该基因的表达 我觉得科学不能有事先的推测的结果,这样容易受思维定势的影响,而忽略了新发现 dongreyuan 我打算用SAB的β-catenin(Ab-37)Antibody,说明
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