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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
A recombinant N-terminal protein fragment from human Clathrin light chain was used as the immunogen for the Clathrin Light Chain antibody.
- 保存条件:
Aliquot and Store at 2-8℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
小鼠
- 应用范围:
Flow, IF, WB, IHC-P
- 抗体英文名:
Clatherin Light Chain Antibody [SPM174]
- 抗体名:
Clatherin Light Chain Antibody [SPM174]
- 规格:
100ug
Clatherin Light Chain 抗体 [SPM174],Clatherin Light Chain Antibody [SPM174],Clatherin Light Chain 抗体 [SPM174],Clatherin Light Chain Antibody [SPM174]
产品名称:Clatherin Light Chain 抗体 [SPM174]-Clatherin Light Chain Antibody [SPM174]
产品货号:PSI-33-667-100ug
产品规格:100ug
背景资料:Recognizes proteins of 31-44kDa, which are identified as Clathrin Light Chains (both A & B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60% homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.
保存建议:Clatherin Light Chain 抗体 [SPM174]-Clatherin Light Chain Antibody [SPM174]Aliquot and Store at 2-8℃
应用类型:Flow, IF, WB, IHC-P
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文献和实验Structure and Properties of Human Immunoglobulin Light-Chain Dimers
Antibodies are multisubunit proteins, but unlike many other multisubunit proteins, it is possible to study structural and functional properties of an antibody subunit free of the others. Thus, antibodies are singular proteins
Analysis of Single Chain Antibody Sequences Using the VBASE2 Fab Analysis Tool
the analysis of multiple rearranged immunoglobulin sequences. In this chapter, we demonstrate the use of the new Fab Analysis – a unique tool that is tailored for the analysis of both heavy and light chain sequences of a given antibody or collection
Guided Selection Methods Through Chain Shuffling
We provide procedures for the panning of fully humanized Fab antibodies using guided selection. Human heavy and light chain genes are amplified. A parental light chain is cloned into a phage display vector and combined with the heavy chain
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