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- ProSci
- 美国
- PSI-33-627-100ug
- 2025年07月12日
- WB, Flow, IF, IHC-P
- 小鼠
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Phytohemagglutinin (PHA)-stimulated peripheral blood cells were used as the immunogen for the CD61 antibody.
- 保存条件：
Aliquot and Store at 2-8℃
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
小鼠
- 应用范围：
WB, Flow, IF, IHC-P
- 抗体英文名：
Integrin beta 3 Antibody [Y2/51]
- 抗体名：
Integrin beta 3 Antibody [Y2/51]
- 规格：
100ug
Integrin beta 3 抗体 [Y2/51]，Integrin beta 3 Antibody [Y2/51]，Integrin beta 3 抗体 [Y2/51],Integrin beta 3 Antibody [Y2/51]
产品名称：Integrin beta 3 抗体 [Y2/51]-Integrin beta 3 Antibody [Y2/51]
产品货号：PSI-33-627-100ug
产品规格：100ug
背景资料：Reacts with human CD61, also called Integrin beta 3 (GPIIIa, vitronectin receptor beta chain). It associates with the alphaV-chain (CD51) to form vitronectin receptor, or with the alphaIIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61). The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow, as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megakaryoblastic leukemia.
保存建议：Integrin beta 3 抗体 [Y2/51]-Integrin beta 3 Antibody [Y2/51]Aliquot and Store at 2-8℃
应用类型：WB, Flow, IF, IHC-P
点击：Integrin beta 3 抗体 [Y2/51]-Integrin beta 3 Antibody [Y2/51]查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验, we may find much more references regarding this issue. http://books.google.com/books?id=3mgPzNFjcWAC&pg=PA51&lpg=PA51&dq=gsk+tyrosine+phosphorylation+and+activity&source=bl&ots=x5ueTldpez&sig=CqRFJleXtEBn9OfelhODPAc28xs&hl=en&ei=KerNSu-XGcem8Abm-qmABA&sa=X&oi=book_result&ct
CD11a/CD11b/CD11c 分子 CDlla 常用单克隆抗体或代号：MHM24， 2F12； CRIS―3(LFA―lα链，整合素α1) 主要表达细胞：Leu[A5] 分子质量(kDa)和结构：spl80(整合素α) 功 能：与1CAM-l(CD54)、ICAM-2(CDl02)、ICAM-3(C1350)结合，介导细胞黏附；与JAMl结合，参与白细胞穿过内皮细胞
由胞膜外区、胞浆区、穿膜区三部分组成。胞浆区一般较短，可能和细胞骨架相联。空膜区富含疏水氨基酸。β亚单位的胞膜外区含有4个富含半胱氨酸的重复序列，靠近外侧N端的40～50kDa的氨基酸残基通过链内二硫键紧密折叠在一起；α亚单位的胞膜外部分有7个同源重复序列，靠近外侧N端的3个或4个重复序列中含有Asp-X-Asp-X-Asp-Gly-X-X-Asp或类似结构，与integrin分子结合二价阳离子（Mg2+）有关，并与β亚单位共同构成粘合素分子的配体
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