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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant human PAX6 protein was used as the immunogen for this antibody.
- 保存条件:
Aliquot and Store at 2-8℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
小鼠
- 应用范围:
WB, Flow, IF
- 抗体英文名:
PAX6 Antibody [PAX6/498]
- 抗体名:
PAX6 Antibody [PAX6/498]
- 规格:
100ug
PAX6 抗体 [PAX6/498],PAX6 Antibody [PAX6/498],PAX6 抗体 [PAX6/498],PAX6 Antibody [PAX6/498]
产品名称:PAX6 抗体 [PAX6/498]-PAX6 Antibody [PAX6/498]
产品货号:PSI-33-183-100ug
产品规格:100ug
背景资料:PAX genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the PAX6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. PAX6 is involved in other anterior segment malformations besides aniridia, such as Peters’ anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The PAX6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human PAX6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
保存建议:PAX6 抗体 [PAX6/498]-PAX6 Antibody [PAX6/498]Aliquot and Store at 2-8℃
应用类型:WB, Flow, IF
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文献和实验mutation db Antithrombin mutation db Asthma and Allergy gene db BIOMDB - Db of mutations causing tetrahydrobiopterin deficiencies BLMbase - Human BLM mutation db (Bloom snydrom) BTKbase - Human BTK mutation db (X-linked
with myc to enhance the Wnt signaling pathway . The long non-coding DNA elements , in a sense long range cis-control elements , had been fine explained in regulating SHH , PAX6 , SOX9 gene spatiotemporal expression . Last month , an article on Nature
genome genetic and physical map data 78. IXDB http://ixdb.mpimg-berlin-dahlem.mpg.de/ Physical maps of human chromosome X 79. RHdb http://www.ebi.ac.uk/RHdb Radiation hybrid map data 80. The Unified Database http://bioinfo.weizmann.ac.il/udb
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