beta-Catenin 抗体-beta-Catenin A

beta-Catenin 抗体，beta-Catenin Antibody，beta-Catenin 抗体,beta-Catenin Antibody

产品名称：beta-Catenin 抗体-beta-Catenin Antibody

产品货号：PSI-33-117-100ug

产品规格：100ug

背景资料：Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. In normal tissues, beta-catenin is localized to the membrane of epithelial cells, consistent with its role in the cell adhesion complex. In breast ductal neoplasia, it is usually localized in cellular membranes. However, in lobular neoplasia, a marked redistribution throughout the cytoplasm results in a diffuse cytoplasmic pattern. Staining with beta-catenin antibody and E-cadherin antibody helps in the accurate identification of ductal and lobular neoplasms, including a distinction between low-grade ductal carcinoma in situ (DCIS) and lobular carcinoma. Additionally, some rectal and gastric adenocarcinomas demonstrate diffuse cytoplasmic staining and a lack of membranous staining, mimicking the staining pattern observed with lobular breast carcinomas.

保存建议：beta-Catenin 抗体-beta-Catenin AntibodyAliquot and Store at 2-8℃

应用类型：WB, Flow, IF, IHC

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