EMAP II 抗体-EMAP II Antibody

EMAP II 抗体，EMAP II Antibody，EMAP II 抗体,EMAP II Antibody

产品名称：EMAP II 抗体-EMAP II Antibody

产品货号：PSI-33-049-100ug

产品规格：100ug

背景资料：EMAP II (Endothelial monocyte-activating polypeptide 2) is a pro-inflammatory cytokine and participant in apoptotic cell death. It is synthesized as a precursor (pro-EMAP II), lacking a secretion signal peptide. In apoptotic cells, the ~34 kDa pro-form of EMAP II is cleaved by Caspase-7 (and Caspase-3 to a lesser extent) at aspartate 144 to its mature, ~20 kDa form. The mature form of EMAP II has been found to have many different functions. In vivo, it recruits leukocytes to the site of apoptotic cell death. In vitro it has been shown to activate endothelial cells (and the release of von Willebrand factor, E-selectin and P-selectin), neutrophils, and induces macrophage expression of TNFa and TF (tissue factor). EMAP II is also a possible biomarker for brain injury, having been found to be differentially expressed in two types: traumatic injury shows an increase and ischemic injury shows a decrease in EMAP II expression (Dave, et al, 2014).

保存建议：EMAP II 抗体-EMAP II AntibodyAliquot and Store at -20℃

应用类型：WB

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