OAZ1 抗体-OAZ1 Antibody

OAZ1 抗体，OAZ1 Antibody，OAZ1 抗体,OAZ1 Antibody

产品名称：OAZ1 抗体-OAZ1 Antibody

产品货号：PSI-22-944-50uL

产品规格：50uL

背景资料：The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs; and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization. Alternatively spliced transcript variants have also been noted for this gene.

保存建议：OAZ1 抗体-OAZ1 AntibodyStore at -20℃

应用类型：WB,IHC

点击：OAZ1 抗体-OAZ1 Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。