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Von Frey (with grids)测痛/炎症/机械痛/痛阈/阈值
Von Frey Hairs 触觉测量套件/纤维丝
Touch test sensory probe/evaluators
美国进口 国内现货
触觉测量套件是由20根尼龙纤维丝组成，英文中称为 Von Frey filaments 或Semmes-Weinstein monofilaments，主要用于评估皮肤的触觉，是非常受欢迎的非侵入式实验器材。它可提供0.008g-300g的刺激力。尼龙丝的粗细及伸出长度决定提供刺激力的大小。实验时，根据实际情况选定一种尼龙丝，调节适当的伸出长度，垂直地刺激皮肤，通过调节伸长、更换尼龙丝可调整刺激力的大小。尼龙丝弯曲以后，持续的推进会导致更多的弯曲，但是刺激力不会再增加。当啮齿类动物得爪受到足够的机械刺激后会有缩回反射，反复调整刺激力的大小，最终选定适当的刺激力。Von Frey 触觉测试不仅可应用于大、小鼠的足底，在临床上也广泛使用，可用于触觉测试及高知觉和低知觉诊断。
另外，可选配凿孔工作台，其网筛孔是利用激光切冲而成的方形孔，尺寸为5×5mm2 ，孔间距约为1mm，这对受试动物而言是一个舒适的环境，也便于操作人员观察动物的足底区域。该凿孔台经涂层处理，便于清洁且不易被腐蚀。
| Color | Evaluator Size | Catalogue item Number | Target Force (grams) | Target Force* (milliNewtons) |
Theoretical Pressure Grams/Sq. mm |
Hand & Dorsal Foot Thresholds | Plantar Threshold |
| Green | 1.65 | 514001 | 0.008 | 0.08 | 2.53 | normal | normal |
| 2.36 | 514002 | 0.02 | 0.20 | 4.39 | normal | normal | |
| 2.44 | 514003 | 0.04 | 0.40 | 4.93 | normal | normal | |
| 2.83 | 514004 | 0.07 | 0.70 | 5.53 | normal | normal | |
| Blue | 3.22 | 514005 | 0.16 | 1.6 | 8.77 | Diminished Light Touch | normal |
| 3.61 | 514006 | 0.40 | 3.9 | 16.1 | Diminished Light Touch | Diminished Light Touch | |
| Purple | 3.84 | 514007 | 0.60 | 5.9 | 18.4 | Diminished Light Touch | Diminished Light Touch |
| 4.08 | 514008 | 1.0 | 9.8 | 24.4 | Diminished Light Touch | Diminished Light Touch | |
| 4.17 | 514009 | 1.4 | 13.7 | 27.9 | Diminished Light Touch | Diminished Light Touch | |
| 4.31 | 514010 | 2.0 | 19.6 | 27.4 | Diminished Light Touch | Diminished Light Touch | |
| Red | 4.56 | 514011 | 4.0 | 39.2 | 40.3 | Loss of Protec-tive Sensation | Diminished Light Touch |
| 4.74 | 514012 | 6.0 | 58.8 | 52.6 | Loss of Protec-tive Sensation | Diminished Light Touch | |
| 4.93 | 514013 | 8.0 | 78.4 | 61.7 | Loss of Protec-tive Sensation | Diminished Light Touch | |
| 5.07 | 514014 | 10 | 98.0 | 68.3 | Loss of Protec-tive Sensation | Loss of Protective Sensation | |
| 5.18 | 514015 | 15 | 147 | 82.0 | Loss of Protec-tive Sensation | Loss of Protective Sensation | |
| 5.46 | 514016 | 26 | 255 | 106 | Loss of Protec-tive Sensation | Loss of Protective Sensation | |
| 5.88 | 514017 | 60 | 588 | 141 | Loss of Protec-tive Sensation | Loss of Protective Sensation | |
| 6.10 | 514018 | 100 | 980 | 193 | Loss of Protec-tive Sensation | Loss of Protective Sensation | |
| 6.45 | 514019 | 180 | 1760 | 222 | Loss of Protec-tive Sensation | Loss of Protective Sensation | |
| Orange | 6.65 | 514020 | 300 | 2940 | 292 | Deep Protective Sensation | Deep Pressure Sensation |
*calculated rounded numbers (conversion factor 9.80665)
参考文献：
Nociceptive behavioural assessments in mouse models of temporomandibular joint disorders
International Journal of Oral Science
The mechanical response threshold of escape behaviour was measured in mice using an ascending, calibrated series of von Frey filaments (North Coast Medical Inc., CA, USA), starting with the smallest filament, with a bending force of 0.008 g (filament size 1.65). Our method was adapted from the ‘rat von Frey test method’, which has been previously published.
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