Beta-TRCP 抗体-Beta-TRCP Antibod

Beta-TRCP 抗体，Beta-TRCP Antibody，Beta-TRCP 抗体,Beta-TRCP Antibody

产品名称：Beta-TRCP 抗体-Beta-TRCP Antibody

产品货号：PSI-16-657-50uL

产品规格：50uL

背景资料：This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class; in addition to an F-box, this protein contains multiple WD-40 repeats. The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu. It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), targeting it for degradation and thus activating nuclear factor kappa-B. Alternatively spliced transcript variants have been described. A related pseudogene exists in chromosome 6.

保存建议：Beta-TRCP 抗体-Beta-TRCP AntibodyStore at -20℃

应用类型：WB,IF

点击：Beta-TRCP 抗体-Beta-TRCP Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。