CBFA2T2 抗体-CBFA2T2 Antibody

CBFA2T2 抗体，CBFA2T2 Antibody，CBFA2T2 抗体,CBFA2T2 Antibody

产品名称：CBFA2T2 抗体-CBFA2T2 Antibody

产品货号：PSI-22-645-50uL

产品规格：50uL

背景资料：In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.

保存建议：CBFA2T2 抗体-CBFA2T2 AntibodyStore at -20℃

应用类型：WB,IF

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