ACO1 抗体-ACO1 Antibody

ACO1 抗体，ACO1 Antibody，ACO1 抗体,ACO1 Antibody

产品名称：ACO1 抗体-ACO1 Antibody

产品货号：PSI-19-974-50uL

产品规格：50uL

背景资料：The protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to iron-responsive elements (IREs), which are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. When the protein binds to IRE, it results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degraded transferrin receptor mRNA. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alternative splicing results in multiple transcript variants

保存建议：ACO1 抗体-ACO1 AntibodyStore at -20℃

应用类型：WB,IHC

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