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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
A synthetic peptide of human H2AFY2
- 保存条件:
Store at 4℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
WB,Flow
- 抗体英文名:
mH2A2 Antibody
- 抗体名:
mH2A2 Antibody
- 规格:
100uL
mH2A2 抗体,mH2A2 Antibody,mH2A2 抗体,mH2A2 Antibody
产品名称:mH2A2 抗体-mH2A2 Antibody
产品货号:PSI-19-071-100uL
产品规格:100uL
背景资料:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and may participate in stable X chromosome inactivation.
保存建议:mH2A2 抗体-mH2A2 AntibodyStore at 4℃
应用类型:WB,Flow
点击:mH2A2 抗体-mH2A2 Antibody查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验of the closest variable (V) and constant (C) domains of immunoglobulins (IG) or antibodies, T cell receptors (TR), and immunoglobulin superfamily (IgSF) proteins, and of the groove (G) domains of major histocompatibility (MH; in humans, HLA for human leukocyte
研究和临床资料均证明,即使主要组织相容性抗原完全相同,仍可能发生程度较轻、较缓慢的排斥反应,提示还存在其他可诱导排斥反应的抗原,即次要组织相容性抗原(minor histocompatibility antigen,mH抗原)。mH抗原表达于机体组织细胞表面,由某些具有多态性的基因编码,可被MHC分子提呈,主要包括以下两类。 (1)性别相关的mH抗原:1955年Eichward和Silmser即已发现,某些近交系小鼠或大鼠中,来源于雄性供者的移植物可被同系雌性受者排斥,而来源于雌性供者的移植
供者的选择是移植排斥反应的防治关键 大量临床资料已证明,器官移植成败主要取决于供、受者间的组织相容性。因此,术前须进行一系列检测,以尽可能选择较理想的供者。 1.红细胞血型检查 人红细胞血型抗原是一种重要的组织相容性抗原,故供者ABO、Rh血型抗原须与受者相同,或至少符合输血原则。 2.受者血清中细胞毒性预存HLA抗体测定 取供者淋巴细胞和受者血清做交叉细胞毒试验,可检出受者血清中是否含有针对供者
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