MBD2 抗体-MBD2 Antibody

MBD2 抗体，MBD2 Antibody，MBD2 抗体,MBD2 Antibody

产品名称：MBD2 抗体-MBD2 Antibody

产品货号：PSI-18-585-50uL

产品规格：50uL

背景资料：DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. Two transcript variants encoding different isoforms have been found for this gene.

保存建议：MBD2 抗体-MBD2 AntibodyStore at -20℃

应用类型：WB,IHC,IF

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