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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ERK2 (NP_620407.1).
- 保存条件:
Store at -20℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
WB,IHC
- 抗体英文名:
ERK2 Antibody, KO Validated
- 抗体名:
ERK2 Antibody, KO Validated
- 规格:
50uL
ERK2 抗体, KO Validated,ERK2 Antibody, KO Validated,ERK2 抗体, KO Validated,ERK2 Antibody, KO Validated
产品名称:ERK2 抗体, KO Validated-ERK2 Antibody, KO Validated
产品货号:PSI-13-090-50uL
产品规格:50uL
背景资料:This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
保存建议:ERK2 抗体, KO Validated-ERK2 Antibody, KO ValidatedStore at -20℃
应用类型:WB,IHC
点击:ERK2 抗体, KO Validated-ERK2 Antibody, KO Validated查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验Methods 2016 年的文章2,国际抗体验证工作小组(International Working Group on Antibody Validation, IWGAV)提出 5 种支柱策略(conceptual pillar),如下:1. 基因策略(敲除验证):利用 CRISPR/Cas 或 RNAi 等技术对靶基因进行敲除(knock out)或敲低(knock down),分别检测对照组与 KO 组的信号。2. 正交策略:在多种样品中使用一种与抗体无关的定量方法,然后比较分析基于抗体的定量
liuxing0626 各位学长好: 我买的ProteinTECH公司的 ERK1 抗体 western blot 条带有两条,公司的说明书也是两条,请问这是个怎么情况?而且我要做ERK1/2。但是ERK2也是单买的,混起来用的话会不会出来3条带了。 ERK1产品地址http://www.ptglab.com/Products/ERK1-Antibody-11257-1-AP.htm liuxing0626
紫苑宝贝 总ERK在哪买?我在santa公司只看到有erk1、erk2和erk5,但没有erk啊?是不是用erk1+erk2来代替啊? 2006010035 这个公司的,我用过比较可以p44/42 MAPK (Erk1/2) Antibody #9102 www.cell signaling .com 无名mm 我也用的cell signaling ,有结果
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