CTCF 抗体-CTCF Antibody

CTCF 抗体，CTCF Antibody，CTCF 抗体,CTCF Antibody

产品名称：CTCF 抗体-CTCF Antibody

产品货号：PSI-13-065-100uL

产品规格：100uL

背景资料：This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

保存建议：CTCF 抗体-CTCF AntibodyStore at 4℃

应用类型：WB,IHC

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