IL-2 抗体 [4N2Q9]-IL-2 Antibody

IL-2 抗体 [4N2Q9]，IL-2 Antibody [4N2Q9]，IL-2 抗体 [4N2Q9],IL-2 Antibody [4N2Q9]

产品名称：IL-2 抗体 [4N2Q9]-IL-2 Antibody [4N2Q9]

产品货号：PSI-11-089-0.1mg

产品规格：0.1mg

背景资料：Interleukin-2 (IL-2) is a O-glycosylated, four alpha -helix bundle cytokine that has potent stimulatory activity for antigen-activated T cells. It is expressed by CD4+ and CD8+ T cells, gamma δ T cells, B cells, dendritic cells, and eosinophils. Mature human IL-2 shares 56% and 66% aa sequence identity with mouse and rat IL-2, respectively. The 55 kDa IL-2 R alpha is specific for IL-2 and binds with low affinity. The 75 kDa IL-2 R beta, which is also a component of the IL-15 receptor, binds IL-2 with intermediate affinity. Upon ligand binding, signal transduction is performed by both IL-2 R beta and gamma c. IL-2 is best known for its autocrine and paracrine activity on T cells. It drives resting T cells to proliferate and induces IL-2 and IL-2 R alpha synthesis. IL-2 plays a central role in the expansion and maintenance of regulatory T cells, although it inhibits the development of Th17 polarized cells.

保存建议：IL-2 抗体 [4N2Q9]-IL-2 Antibody [4N2Q9] stored at 2℃ to -8℃ for one month without detectable loss of activity

应用类型：E

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