VISTA 抗体-VISTA Antibody

VISTA 抗体，VISTA Antibody，VISTA 抗体,VISTA Antibody

产品名称：VISTA 抗体-VISTA Antibody

产品货号：PSI-8695-0.02mg

产品规格：0.02mg

背景资料：The lymphocyte activation gene-3 (LAG3) is a member of the immunoglobulin superfamily and binds MHC class II with high affinity (1), negatively regulating T-cell function and homeostasis (2). It is expressed in B, T, and NK cells, monocytes, and dendritic cells (3), and acts to regulate T cell expansion (4). LAG3 is also an important immune checkpoint protein, with anti-LAG3 antibodies activating T effector cells and affecting regulatory T cell functions. Furthermore LAG3 appears to act in a synergistic fashion with PD-1/PD-L1, suggesting that a dual antibody approach may prove useful in cancer immunotherapy (5).

保存建议：VISTA 抗体-VISTA Antibody stored at 4℃ for three months and -20℃, stable for up to one year

应用类型：E, WB, IHC, ICC, IF

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